Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems
The hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yea...
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| Other Authors: | , |
| Format: | article |
| Language: | eng |
| Published: |
2003
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| Subjects: | |
| Online Access: | http://hdl.handle.net/1822/1692 |
| Country: | Portugal |
| Oai: | oai:repositorium.sdum.uminho.pt:1822/1692 |
| Summary: | The hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yeast biomass at different loadings up to 21 % (v/v) were used in order to mimic the solid phase of conventional high cell density systems. The main hydrodynamic parameters – liquid circulation velocity, gas and solids holdups in all reactor sections have been measured and experimental values were satisfactorily predicted using an appropriate three-phase model. The results of this study may beapplied to suggest the optimal design (in terms of hydrodynamic behaviour) of a batch/continuous three-phase ALR for high cell density fermentations. |
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