Genetic defects in fungal recognition and susceptibility to invasive pulmonary aspergillosis

The interindividual variability in the onset and clinical course of invasive pulmonary aspergillosis (IPA) raises fundamental questions about its actual pathogenesis. Clinical and epidemiological studies have reported only a few examples of monogenic defects, however an expanding number of common po...

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Bibliographic Details
Main Author: Cunha, Cristina Amorim (author)
Other Authors: Carvalho, Agostinho (author)
Format: article
Language:eng
Published: 2019
Subjects:
Aspergillus
Genetic Variation
Humans
Invasive Pulmonary Aspergillosis
Receptors, Pattern Recognition
Genetic Predisposition to Disease
Immunity, Innate
Single nucleotide polymorphism (SNP)
Innate immunity
Immunocompromised host
Fungal recognition
Pattern recognition receptor
Personalized medicine
Science & Technology
Online Access:https://hdl.handle.net/1822/62293
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/62293

Internet

https://hdl.handle.net/1822/62293

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