Novel heterocyclic quinoline/quinolone-based compounds as acetylcholinesterase inhibitors and antioxidant agents

Alzheimer’s disease represents about 60-80% of all cases of dementia, mainly affecting people over 65 years. This pathology is caracterizated at the molecular level by the presence of senile plaques (Aβ amyloid peptides aggregates) and neurofibrillary tangles (NFTs). In addition, several experimenta...

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Bibliographic Details
Main Author: Ferreira, João Paulo de Sousa (author)
Format: masterThesis
Language:eng
Published: 2019
Subjects:
Alzheimer’s disease
Oxidative stress
Acetylcholinesterase
Antioxidants
Aβ peptides
Tau-protein
Neurofibrillary tangles
Furo[3,2-c]quinolines
Pyrazoles
Isoxazoles
Online Access:http://hdl.handle.net/10773/30140
Country:Portugal
Oai:oai:ria.ua.pt:10773/30140

Internet

http://hdl.handle.net/10773/30140

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