Microscale flow dynamics of red blood cells in a circular microchannel

The blood flow dynamics in microcirculation depends strongly on the motion, deformation and interaction of RBCs within the microvessel. This paper presents the application of a confocal micro-PTV system to track RBCs through a circular polydimethysiloxane (PDMS) microchannel. This technique, consist...

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Bibliographic Details
Main Author: Lima, R. (author)
Other Authors: Nakamura, M. (author), Ishikawa, Takuji (author), Tanaka, S. (author), Takeda, Motohiro (author), Imai, Yohsuke (author), Tsubota, Ken-ichi (author), Wada, Shigeo (author), Yamaguchi, Takami (author)
Format: conferenceObject
Language:eng
Published: 2011
Subjects:
Blood flow
Microcirculation
Online Access:http://hdl.handle.net/10198/4981
Country:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/4981
Description
Summary:The blood flow dynamics in microcirculation depends strongly on the motion, deformation and interaction of RBCs within the microvessel. This paper presents the application of a confocal micro-PTV system to track RBCs through a circular polydimethysiloxane (PDMS) microchannel. This technique, consists of a spinning disk confocal microscope, high speed camera and a diode-pumped solid state (DPSS) laser combined with a single particle tracking (SPT) method. By using this system detailed motions of individual RBCs were measured at a microscale level. Our results showed that this technique can provide detailed information about microscale disturbance effects caused by RBCs in flowing blood.

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