Biological evaluation of naproxen–dehydrodipeptide conjugates with self-hydrogelation capacity as dual LOX/COX inhibitors

The use of peptide–drug conjugates is emerging as a powerful strategy for targeted drug delivery. Previously, we have found that peptides conjugated to a non-steroidal anti-inflammatory drug (NSAID), more specifically naproxen–dehydrodipeptide conjugates, readily form nanostructured fibrilar supramo...

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Bibliographic Details
Main Author: Moreira, Rute (author)
Other Authors: Jervis, Peter John (author), Carvalho, André (author), Ferreira, Paula M. T. (author), Martins, J. A. R. (author), Valentão, Patrícia (author), Andrade, Paula B. (author), Pereira, David M. (author)
Format: article
Language:eng
Published: 2020
Subjects:
anti-inflammatory
hydrogel
dehydrodipeptide
cyclooxygenase
lipoxygenase
cancer
proteasome
Science & Technology
Online Access:http://hdl.handle.net/1822/64442
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/64442

Internet

http://hdl.handle.net/1822/64442

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