theLiTE™: a screening platform to identify compounds that reinforce tight junctions

Tight junctions (TJ) are formed by transmembrane and intracellular proteins that seal the intercellular space and control selective permeability of epithelia. Integrity of the epithelial barrier is central to tissue homeostasis and barrier dysfunction has been linked to many pathological conditions....

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Bibliographic Details
Main Author: Gomes, Teresa Lopes (author)
Other Authors: Oliveira-Marques, Virgínia de (author), Hampson, Richard John (author), Jacinto, António (author), de Moraes, Luciana Vieira (author), Martinho, Rui Goncalo (author)
Format: article
Language:eng
Published: 2022
Subjects:
PAR-6
Epithelial cells
Tight junctions
Quercetin
Myricetin
Polarity (cell)
Online Access:http://hdl.handle.net/10400.1/17563
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/17563

Internet

http://hdl.handle.net/10400.1/17563

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