Lipid nanoparticles biocompatibility and cellular uptake in a 3D human lung model
Aim: Design nanostructured lipid carriers (NLC) to facilitate drug delivery to tuberculosis-infected areas, exploiting macrophage mannose receptors and assess their uptake in a 3D human lung model. Materials & methods: NLCs and mannosylated-NLCs were synthetized and characterized. Their uptake a...
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Format: | masterThesis |
Language: | por |
Published: |
2020
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Online Access: | https://hdl.handle.net/10216/128679 |
Country: | Portugal |
Oai: | oai:repositorio-aberto.up.pt:10216/128679 |