Candida auris: a quick review on identification, current treatments, and challenges

Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming...

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Detalhes bibliográficos
Autor principal: Cernáková, Lucia (author)
Outros Autores: Roudbary, Maryam (author), Brás, Susana Maria Pereira (author), Tafaj, Silva (author), Rodrigues, Célia F. (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Texto completo:http://hdl.handle.net/1822/72487
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/72487
Descrição
Resumo:Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming biofilms (naturally more resistant to drugs) has made treatments of C. auris infections highly difficult. This review intends to quickly illustrate the main issues in C. auris identification, available treatments and the associated mechanisms of resistance, and the novel and alternative treatment and drugs (natural and synthetic) that have been recently reported. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.