Carboxymethylchitosan/poly (amidoamine) dendrimer nanoparticles in central nervous systems-regenerative medicine: effects on neuron/glial cell viability and internalization efficiency

The applicability of CMCht/PAMAM dendrimer nanoparticles for CNS applications was investigated. AFM and TEM observations revealed that the nanoparticles possessed a nanosphere- like shape with a size from 22.0 to 30.7 nm. The nanoparticles could be bound to fluorescent-probe FITC for tracing purpose...

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Bibliographic Details
Main Author: Salgado, A. J. (author)
Other Authors: Oliveira, Joaquim M. (author), Pirraco, Rogério (author), Pereira, Vitor H. (author), Fraga, J. S. (author), Marques, A. P. (author), Neves, N. M. (author), Mano, J. F. (author), Reis, R. L. (author), Sousa, Nuno (author)
Format: article
Language:eng
Published: 2010
Subjects:
Cell viability
Dendrimers
Glial cells
Internalization
Intracellular drug delivery systems
Science & Technology
Online Access:http://hdl.handle.net/1822/20648
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/20648

Internet

http://hdl.handle.net/1822/20648

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