Carboxymethylchitosan/poly (amidoamine) dendrimer nanoparticles in central nervous systems-regenerative medicine: effects on neuron/glial cell viability and internalization efficiency

The applicability of CMCht/PAMAM dendrimer nanoparticles for CNS applications was investigated. AFM and TEM observations revealed that the nanoparticles possessed a nanosphere- like shape with a size from 22.0 to 30.7 nm. The nanoparticles could be bound to fluorescent-probe FITC for tracing purpose...

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Detalhes bibliográficos
Autor principal: Salgado, A. J. (author)
Outros Autores: Oliveira, Joaquim M. (author), Pirraco, Rogério (author), Pereira, Vitor H. (author), Fraga, J. S. (author), Marques, A. P. (author), Neves, N. M. (author), Mano, J. F. (author), Reis, R. L. (author), Sousa, Nuno (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Cell viability
Dendrimers
Glial cells
Internalization
Intracellular drug delivery systems
Science & Technology
Texto completo:http://hdl.handle.net/1822/20648
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/20648

Texto Completo

http://hdl.handle.net/1822/20648

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