Liquified chitosan-alginate multilayer capsules incorporating poly(L-lactic acid) microparticles as cell carriers

We report the development of liquified multilayer hierarchical capsules capable of providing cell adhesion sites to the encapsulated cells. The proof of principle is demonstrated with the example of a chitosan–alginate shell via layer-by-layer assembly, encapsulating cells adhered to the functionali...

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Bibliographic Details
Main Author: Correia, Clara R. (author)
Other Authors: Praveen, S. (author), Reis, R. L. (author), Mano, J. F. (author)
Format: article
Language:eng
Published: 2013
Subjects:
Bioencapsulation
Cell adhesion
Layer-by-layer
Microcarriers
Natural polymers
Online Access:http://hdl.handle.net/1822/23280
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/23280
Description
Summary:We report the development of liquified multilayer hierarchical capsules capable of providing cell adhesion sites to the encapsulated cells. The proof of principle is demonstrated with the example of a chitosan–alginate shell via layer-by-layer assembly, encapsulating cells adhered to the functionalized surface of poly(L-lactic acid) microparticles.

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