In vitro 3D cell sheet-based model for unraveling scar pathophysiology

Fibroblasts are key players in the scarring process. In hypertrophic scars, fibroblasts suffer phenotypical changes into myofibroblasts persisting in the wound under the influence of local biochemical (TGFb1) and biomechanical signaling leading to enhanced immature extracellular matrix (ECM) synthes...

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Bibliographic Details
Main Author: Rodrigues, Daniel Barreira (author)
Other Authors: Moreira, Helena Rocha (author), Reis, R. L. (author), Marques, A. P. (author)
Format: conferenceObject
Language:eng
Published: 2017
Subjects:
Cell sheet technology
Scarring
Skin models
Ciências Médicas::Medicina Clínica
Online Access:http://hdl.handle.net/1822/51923
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/51923

Internet

http://hdl.handle.net/1822/51923

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