Ethylazinphos Interaction with Membrane Lipid Organization Induces Increase of Proton Permeability and Impairment of Mitochondrial Bioenergetic Functions

Ethylazinphos increases the passive proton permeability of lipid bilayers reconstituted with dipalmitoylphosphatidylcholine (DPPC) and mitochondrial lipids. A sharp increase of proton permeability is detected at insecticide/lipid molar ratios identical to those inducing phase separation in the plane...

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Bibliographic Details
Main Author: Videira, Romeu A. (author)
Other Authors: Antunes-Madeira, Maria C. (author), Madeira, Vítor M. C. (author)
Format: article
Language:eng
Published: 2001
Subjects:
ethylazinphos; membrane organization; proton permeability; mitochondrial respiration; transmembrane potential; oxidative phosphorylation
Online Access:http://hdl.handle.net/10316/5425
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5425

Internet

http://hdl.handle.net/10316/5425

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