5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion

Background. Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in the development of ischemia/reperfusion (I/R) injury. The aim of this study was to investigate the effects of a water-soluble and potent PARP inhibitor, 5-aminoisoquinolino...

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Bibliographic Details
Main Author: Chatterjee, PK (author)
Other Authors: Chatterjee, BE (author), Pedersen, H (author), Sivarajah, A (author), McDonald, MC (author), Mota-Filipe, H (author), Brown, PAJ (author), Stewart, KN (author), Cuzzocrea, S (author), Threadgill, MD (author), Thiemermann, C (author)
Format: article
Language:eng
Published: 2015
Subjects:
Urology & Nephrology
Online Access:http://hdl.handle.net/10451/21227
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21227

Internet

http://hdl.handle.net/10451/21227

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