Cell–fibronectin interactions and actomyosin contractility regulate the segmentation clock and spatio-temporal somite cleft formation during chick embryo somitogenesis

Fibronectin is essential for somite formation in the vertebrate embryo. Fibronectin matrix assembly starts as cells emerge from the primitive streak and ingress in the unsegmented presomitic mesoderm (PSM). PSM cells undergo cyclic waves of segmentation clock gene expression, followed by Notch-depen...

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Bibliographic Details
Main Author: Gomes De Almeida, Patrícia (author)
Other Authors: Rifes, Pedro (author), Jesus, Ana Patrícia (author), Pinheiro, Gonçalo (author), P. Andrade, Raquel (author), Thorsteinsdóttir, Sólveig (author)
Format: article
Language:eng
Published: 2022
Subjects:
Online Access:http://hdl.handle.net/10400.1/17999
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/17999