Lysine deacetylases and mitochondrial dynamics in neurodegeneration

Lysine acetylation is a key post-translational modification known to regulate gene transcription, signal transduction, cellular transport and metabolism. Lysine deacetylases (KDACs), including classical KDACs (a.k.a. histone deacetylases; HDACs) and sirtuins (SIRTs), are emerging therapeutic targets...

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Bibliographic Details
Main Author: Pedro Guedes-Dias (author)
Other Authors: Jorge M A Oliveira (author)
Format: other
Language:eng
Published: 2013
Subjects:
Online Access:https://repositorio-aberto.up.pt/handle/10216/104625
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/104625