Lysine deacetylases and mitochondrial dynamics in neurodegeneration
Lysine acetylation is a key post-translational modification known to regulate gene transcription, signal transduction, cellular transport and metabolism. Lysine deacetylases (KDACs), including classical KDACs (a.k.a. histone deacetylases; HDACs) and sirtuins (SIRTs), are emerging therapeutic targets...
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Format: | other |
Language: | eng |
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2013
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Online Access: | https://repositorio-aberto.up.pt/handle/10216/104625 |
Country: | Portugal |
Oai: | oai:repositorio-aberto.up.pt:10216/104625 |