Endogenous Cerberus activity is required for anterior head specification in Xenopus

We analyzed the endogenous requirement for Cerberus in Xenopus head development. 'Knockdown' of Cerberus function by antisense morpholino oligonucleotides did not impair head formation in the embryo. In contrast, targeted increase of BMP, Nodal and Wnt signaling in the anterior dorsal-endo...

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Bibliographic Details
Main Author: Silva, Ana Cristina (author)
Other Authors: Filipe, Mário (author), Kuerner, Klaus-Michael (author), Steinbeisser, Herbert (author), Belo, José A. (author)
Format: article
Language:eng
Published: 2018
Subjects:
Spemann organizer
Visceral endoderm
Transcription factor
Primitive endoderm
Secreted proteins
Gene
Expression
Induction
Mouse
Gastrulation
Cerberus
Head induction
Morpholino
Targeted activation
Xenopus laevis
Online Access:http://hdl.handle.net/10400.1/11850
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11850

Internet

http://hdl.handle.net/10400.1/11850

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