CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

Accurate chromosome segregation during mitosis requires precise coordination of various processes such as chromosome alignment, maturation of proper kinetochoremicrotubule (kMT) attachments, correction of erroneous attachments, and silencing of the spindle assembly checkpoint (SAC). How these fundam...

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Detalhes bibliográficos
Autor principal: Manning, AL (author)
Outros Autores: Bakhoum, SF (author), Maffini, S (author), Melo, CC (author), Maiato, H (author), Compton, DA (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Cell cycle proteins
Cell Line
Tumor
Chromosomes
Microtubules
Mitosis
Mitotic spindle apparatus
Recombinant Fusion Proteins
Texto completo:http://hdl.handle.net/10216/53790
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/53790

Texto Completo

http://hdl.handle.net/10216/53790

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