Analysis of pro-apoptotic protein trafficking to and from mitochondria
Mitochondria play a key role in cell death and its regulation. The permeabilization of the outer mitochondrial membrane which is mainly controlled by proteins of the BCL-2 family, is a key event that can be directly induced by p53 and results in the release of pro-apoptotic factors to the cytosol, s...
Autor principal: | |
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Outros Autores: | , , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2015
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10316/41110 |
País: | Portugal |
Oai: | oai:estudogeral.sib.uc.pt:10316/41110 |