Analysis of pro-apoptotic protein trafficking to and from mitochondria

Mitochondria play a key role in cell death and its regulation. The permeabilization of the outer mitochondrial membrane which is mainly controlled by proteins of the BCL-2 family, is a key event that can be directly induced by p53 and results in the release of pro-apoptotic factors to the cytosol, s...

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Detalhes bibliográficos
Autor principal: Vega-Naredo, Ignacio (author)
Outros Autores: Cunha-Oliveira, Teresa (author), Serafim, Teresa L. (author), Sardão, Vilma A. (author), Oliveira, Paulo J. (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Texto completo:http://hdl.handle.net/10316/41110
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/41110