Synthesis and host recognition of Staphylococcus aureus peptidoglycan

"Bacteria are able to establish relationships with other organisms, which may be temporary, as in a bacterial infection, or long-term, as in symbiosis. From the interplay between different organisms emerged the concept of “identity”, i.e. the need to distinguish “self” from “non-self”. Multicel...

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Detalhes bibliográficos
Autor principal: Covas, Gonçalo (author)
Formato: doctoralThesis
Idioma:eng
Publicado em: 2020
Assuntos:
Texto completo:http://hdl.handle.net/10362/98834
País:Portugal
Oai:oai:run.unl.pt:10362/98834
Descrição
Resumo:"Bacteria are able to establish relationships with other organisms, which may be temporary, as in a bacterial infection, or long-term, as in symbiosis. From the interplay between different organisms emerged the concept of “identity”, i.e. the need to distinguish “self” from “non-self”. Multicellular organisms have developed immune systems responsible for the detection of “non-self” organisms that lead to the activation of appropriate responses to maintain the organism in a state of homeostasis. In opposition, bacteria have developed mechanisms (virulence factors) to avoid their identification as harmful, in order to assure their survival within the host. (...)"