Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release

Colorectal carcinoma (CRC) is one of the most common causes of cancer-related mortality. Short-chain fatty acids secreted by dietary propionibacteria from the intestine, such as acetate, induce apoptosis in CRC cells and may therefore be relevant in CRC prevention and therapy. We previously reported...

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Bibliographic Details
Main Author: Marques, Carolina (author)
Other Authors: Oliveira, C. Suellen F. (author), Alves, Sara (author), Chaves, S. R. (author), Coutinho, O. P. (author), Côrte-Real, Manuela (author), Preto, Ana (author)
Format: article
Language:eng
Published: 2013
Subjects:
Colorectal carcinoma
Cathepsin-D
Lisosomal membrane permeabilization
Apoptosis
Acetate
lysosomal membrane permeabilization (LMP)
Science & Technology
Online Access:http://hdl.handle.net/1822/23595
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/23595

Internet

http://hdl.handle.net/1822/23595

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