3D tumor spheroids: an overview on the tools and techniques used for their analysis

In comparison with 2D cell culture models, 3D spheroids are able to accurately mimic some features of solid tumors, such as their spatial architecture, physiological responses, secretion of soluble mediators, gene expression patterns and drug resistance mechanisms. These unique characteristics highl...

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Bibliographic Details
Main Author: Costa, Elisabete Cristina da Rocha (author)
Other Authors: Moreira, André Ferreira (author), Diogo, Duarte Miguel de Melo (author), Gaspar, Vítor Manuel Abreu (author), Carvalho, Marco António Paulo de (author), Correia, I.J. (author)
Format: article
Language:eng
Published: 2018
Subjects:
3D tumor spheroids
Cancer therapy
In vitro models
Methodologies
Therapeutic screening
Online Access:http://hdl.handle.net/10400.6/4690
Country:Portugal
Oai:oai:ubibliorum.ubi.pt:10400.6/4690

Internet

http://hdl.handle.net/10400.6/4690

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