Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: Brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug

The first anti-HIV drug, zidovudine (AZT), was approved by the FDA a quarter of a century ago, in 1985. Currently, anti-HIV drug-combination therapies only target HIV-1 protease and reverse transcriptase. Unfortunately, most of these molecules present numerous shortcoming; such as viral resistances...

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Detalhes bibliográficos
Autor principal: Catia Teixeira (author)
Outros Autores: Jose R B Gomes (author), Paula Gomes (author), Francois Maurel (author)
Formato: other
Idioma:eng
Publicado em: 2011
Assuntos:
Texto completo:https://hdl.handle.net/10216/82028
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/82028