Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: Brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug

The first anti-HIV drug, zidovudine (AZT), was approved by the FDA a quarter of a century ago, in 1985. Currently, anti-HIV drug-combination therapies only target HIV-1 protease and reverse transcriptase. Unfortunately, most of these molecules present numerous shortcoming; such as viral resistances...

Full description

Bibliographic Details
Main Author: Catia Teixeira (author)
Other Authors: Jose R B Gomes (author), Paula Gomes (author), Francois Maurel (author)
Format: other
Language:eng
Published: 2011
Subjects:
Online Access:https://hdl.handle.net/10216/82028
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/82028