Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: Brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug
The first anti-HIV drug, zidovudine (AZT), was approved by the FDA a quarter of a century ago, in 1985. Currently, anti-HIV drug-combination therapies only target HIV-1 protease and reverse transcriptase. Unfortunately, most of these molecules present numerous shortcoming; such as viral resistances...
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Other Authors: | , , |
Format: | other |
Language: | eng |
Published: |
2011
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Subjects: | |
Online Access: | https://hdl.handle.net/10216/82028 |
Country: | Portugal |
Oai: | oai:repositorio-aberto.up.pt:10216/82028 |