Combination of PLGA nanoparticles with mucoadhesive guar-gum films for buccal delivery of antihypertensive peptide

Oral administration of proteins and peptides still is a challenging task to overcome due to low permeability through absorptive epithelia, degradation and metabolism that lead to poor bioavailability. Attempting to overcome such limitations, an antihypertensive peptide derived from whey protein, wit...

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Bibliographic Details
Main Author: Castro, Pedro M. (author)
Other Authors: Baptista, Patrícia (author), Madureira, Ana Raquel (author), Sarmento, Bruno (author), Pintado, Manuela E. (author)
Format: article
Language:eng
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10400.14/25688
Country:Portugal
Oai:oai:repositorio.ucp.pt:10400.14/25688