Domain-dependent evolution explains functional homology of protostome and deuterostome complement C3-like proteins

Complement proteins emerged early in evolution but outside the vertebrate clade they are poorly characterized. An evolutionary model of C3 family members revealed that in contrast to vertebrates the evolutionary trajectory of C3-like genes in cnidarian, protostomes and invertebrate deuterostomes was...

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Bibliographic Details
Main Author: Peng, Maoxiao (author)
Other Authors: Li, Zhi (author), Cardoso, João (author), Niu, Donghong (author), Liu, Xiaojun (author), Dong, Zhiguo (author), Li, Jiale (author), Power, Deborah (author)
Format: article
Language:eng
Published: 2022
Subjects:
Conserved domain
Functional homologues
Parallel evolution
Complement C3
C4
C5 family
C3-like protein a-subunit
Online Access:http://hdl.handle.net/10400.1/18274
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/18274

Internet

http://hdl.handle.net/10400.1/18274

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