QSAR-driven design and discovery of novel compounds with antiplasmodial and transmission blocking activities

Malaria is a life-threatening infectious disease caused by parasites of the genus Plasmodium, affecting more than 200 million people worldwide every year and leading to about a half million deaths. Malaria parasites of humans have evolved resistance to all current antimalarial drugs, urging for the...

ver descrição completa

Detalhes bibliográficos
Autor principal: Lima, Marilia N.N. (author)
Outros Autores: Melo-Filho, Cleber C. (author), Cassiano, Gustavo C. (author), Neves, Bruno J. (author), Alves, Vinicius M. (author), Braga, Rodolpho C. (author), Cravo, Pedro V.L. (author), Muratov, Eugene N. (author), Calit, Juliana (author), Bargieri, Daniel Y. (author), Costa, Fabio T.M. (author), Andrade, Carolina H. (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
DUTPase
Malaria
Plasmodium falciparum
QSAR
Transmission blocker
Virtual screening
Pharmacology
Pharmacology (medical)
Drug Discovery
SDG 3 - Good Health and Well-being
Texto completo:http://hdl.handle.net/10362/116841
País:Portugal
Oai:oai:run.unl.pt:10362/116841

Texto Completo

http://hdl.handle.net/10362/116841

Registros relacionados