Development of an in vitro cell system from zebrafish suitable to study bone cell differentiation and extracellular matrix mineralization

Mechanisms of bone formation and skeletal development have been successfully investigated in zebrafish using a variety of in vivo approaches, but in vitro studies have been hindered due to a lack of homologous cell lines capable of producing an extracellular matrix (ECM) suitable for mineral deposit...

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Bibliographic Details
Main Author: Vijayakumar, Parameswaran (author)
Other Authors: Laizé, Vincent (author), Cardeira Da Silva, João (author), Trindade, Marlene (author), Cancela, M. Leonor (author)
Format: article
Language:eng
Published: 2018
Subjects:
Alkaline phosphatase activity
Danio rerio
Stem cells
Gene expression
Osteoblastic differentiation
Retinoic acid
Sparus aurata
Collagen gene
Gla protein
Fish
Online Access:http://hdl.handle.net/10400.1/11250
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11250

Internet

http://hdl.handle.net/10400.1/11250

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