An insight into the synthesis of cationic porphyrin-imidazole derivatives and their photodynamic inactivation efficiency against Escherichia coli

New porphyrin-imidazole derivatives were synthesised by Radziszewski reaction between 2-formyl-5,10,15,20-tetraphenylporphyrin 1 and several (hetem)aromatic 1,2-diones, which after cationization afforded promising monocationic photosensitizers 3a-d. Singlet oxygen studies have demonstrated that all...

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Bibliographic Details
Main Author: Moreira, Xavier (author)
Other Authors: Santos, Patricia (author), Faustino, M. Amparo F. (author), Raposo, M. Manuela M. (author), Costa, Susana P. G. (author), Moura, Nuno M. M. (author), Gomes, Ana T. P. C. (author), Almeida, Adelaide (author), Neves, M. G. P. M. S. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Porphyrin
N-Heterocycles
Photosensitizer
Antimicrobial photodynamic therapy
Gram-negative E. coli
Ciências Naturais::Ciências Químicas
Science & Technology
Online Access:http://hdl.handle.net/1822/66002
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/66002

Internet

http://hdl.handle.net/1822/66002

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