Presmoothed Landmark estimators of the transition probabilities

Multi-state models can be successfully used to model complicated event history data, for example, describing stages in the disease progression of a patient. In these models one important goal is the estimation of the transition probabilities since they allow for long term prediction of the process....

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Bibliographic Details
Main Author: Machado, Luís Meira (author)
Format: conferencePaper
Language:eng
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/1822/45377
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/45377
Description
Summary:Multi-state models can be successfully used to model complicated event history data, for example, describing stages in the disease progression of a patient. In these models one important goal is the estimation of the transition probabilities since they allow for long term prediction of the process. There have been several recent contributions for the estimation of the transition probabilities. Recently, de Uña- Álvarez and Meira-Machado (2015) proposed new estimators for these quantities, and their superiority with respect to the competing estimators has been proved in situations in which the Markov condition is violated. In this paper, we propose a modification of the estimator proposed by de Uña-Álvarez and Meira-Machado based on presmoothing. Simulations show that the presmoothed estimators may be much more efficient than the completely nonparametric estimator.