Chiral separation of flurbiprofen enantiomers by preparative and simulated moving bed chromatography

This study presents the chiral resolution of flurbiprofen enantiomers by preparative liquid chromatography using the simulated moving bed (SMB) technology. Flurbiprofen enantiomers are widely used as nonsteroidal anti-inflammatory drugs, and although demonstrate different therapeutic actions, they a...

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Bibliographic Details
Main Author: Ribeiro, António E. (author)
Other Authors: Gomes, Pedro Sá (author), Pais, Luís S. (author), Rodrigues, Alírio (author)
Format: article
Language:eng
Published: 2011
Subjects:
Chiral separations
Pharmaceutical intermediate
Flurbiprofen enantiomers
Preparative chiral separation
Simulated moving bed chromatography
Online Access:http://hdl.handle.net/10198/6342
Country:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/6342

Internet

http://hdl.handle.net/10198/6342

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