Uncovering differential DNA methylation alterations in subtypes of Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a hematological malignancy where the hematopoietic stem cells or progenitor cells accumulate epigenetic and genetic alterations, losing their differentiation ability and gain proliferative advantage. AML is classified based on the cytogenetic abnormalities detected in...

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Bibliographic Details
Main Author: Cardoso, Cândida Patrícia Valente (author)
Format: masterThesis
Language:eng
Published: 2021
Subjects:
Leucemia mielóide aguda
Grupo de risco intermédio
Biomarcadores de prognóstico
Expressão génica
Metilação de dna
Domínio/Área Científica::Ciências Médicas::Outras Ciências Médicas
Online Access:http://hdl.handle.net/10400.1/16336
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/16336

Internet

http://hdl.handle.net/10400.1/16336

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