Contact sensitizer nickel sulfate activates the transcription factors NF-kB and AP-1 and increases the expression of nitric oxide synthase in a skin dendritic cell line

Nuclear factor kappa B (NF-kB) and activating protein-1 (AP-1) transcription factors are ubiquitously expressed signaling molecules known to regulate the transcription of a large number of genes involved in immune responses, namely the inducible isoform of nitric oxide synthase (iNOS). In this study...

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Bibliographic Details
Main Author: Cruz, MT (author)
Other Authors: Gonçalo, Margarida (author), Figueiredo, A (author), Carvalho, AP (author), Duarte, CB (author)
Format: article
Language:eng
Published: 2010
Subjects:
Células Dendríticas
NF-kappa B
Pele
Sintetase de Óxido Nítrico
Níquel
Online Access:http://hdl.handle.net/10400.4/764
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/764

Internet

http://hdl.handle.net/10400.4/764

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