Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation

On the basis of population genomic and phylogeographic analyses of 1669 Mycobacterium tuberculosis lineage 4 (L4) genomes, we find that dispersal of L4 has been completely dominated by historical migrations out of Europe. We demonstrate an intimate temporal relationship between European colonial exp...

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Bibliographic Details
Main Author: Brynildsrud, Ola B. (author)
Other Authors: Pepperell, Caitlin S. (author), Suffys, Philip (author), Grandjean, Louis (author), Monteserin, Johana (author), Debech, Nadia (author), Bohlin, Jon (author), Alfsnes, Kristian (author), Pettersson, John O.H. (author), Kirkeleite, Ingerid (author), Fandinho, Fatima (author), da Silva, Marcia Aparecida (author), Perdigao, Joao (author), Portugal, Isabel (author), Viveiros, Miguel (author), Clark, Taane (author), Caws, Maxine (author), Dunstan, Sarah (author), Thai, Phan Vuong Khac (author), Lopez, Beatriz (author), Ritacco, Viviana (author), Kitchen, Andrew (author), Brown, Tyler S. (author), van Soolingen, Dick (author), O'Neill, Mary B. (author), Holt, Kathryn E. (author), Feil, Edward J. (author), Mathema, Barun (author), Balloux, Francois (author), Eldholm, Vegard (author)
Format: article
Language:eng
Published: 2021
Subjects:
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Ecology, Evolution, Behavior and Systematics
Infectious Diseases
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/116688
Country:Portugal
Oai:oai:run.unl.pt:10362/116688

Internet

http://hdl.handle.net/10362/116688

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