Acute kidney injury associated with COVID-19 infection: a case report

ABSTRACT SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. K...

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Bibliographic Details
Main Author: Duarte,Tiago (author)
Other Authors: Caeiro,Fernando (author), Góis,Mário (author), Matos,António (author), Viana,Helena (author), Vieira,César (author), Paulos,Jorge (author), Paixão,Paulo (author), Matos,Bruno (author), Germano,Nuno (author), Nolasco,Fernando (author)
Format: report
Language:eng
Published: 2021
Subjects:
acute kidney injury
COVID-19
kidney biopsy
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692021000300192
Country:Portugal
Oai:oai:scielo:S0872-01692021000300192
Description
Summary:ABSTRACT SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.

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