Zirconia-doped nanoparticles: organic coating, polymeric entrapment and application as dual-imaging agents

Zirconia nanoparticles doped with Eu3+, Tb3+ and Gd3+ ions have been synthesized following the benzyl alcohol route. The nanoparticles were coated with N-hydroxydodecanamide and encapsulated in PLGA-b-PEG-COOH nanomicelles. The magnetic and fluorescent properties of these hybrid nanocarriers were in...

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Bibliographic Details
Main Author: Rebuttini, Valentina (author)
Other Authors: Pucci, Andrea (author), Arosio, Paolo (author), Bai, Xue (author), Locatelli, Erica (author), Pinna, Nicola (author), Lascialfari, Alessandro (author), Franchini, Mauro Comes (author)
Format: article
Language:eng
Published: 1000
Subjects:
ONE-STEP SYNTHESIS
OPTICAL SPECTROSCOPY
ZRO2 NANOCRYSTALS
CONTRAST AGENTS
SCALE SYNTHESIS
DRUG-DELIVERY
OXIDE
PHOTOLUMINESCENCE
NANOCOMPOSITES
TOXICITY
Online Access:http://hdl.handle.net/10773/20632
Country:Portugal
Oai:oai:ria.ua.pt:10773/20632
Description
Summary:Zirconia nanoparticles doped with Eu3+, Tb3+ and Gd3+ ions have been synthesized following the benzyl alcohol route. The nanoparticles were coated with N-hydroxydodecanamide and encapsulated in PLGA-b-PEG-COOH nanomicelles. The magnetic and fluorescent properties of these hybrid nanocarriers were investigated, proving them to be potential dual-imaging contrast agents.

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