BDNF receptor cleavage : relevance for Alzheimer’s disease pathophysiology

Alzheimer’s Disease (AD) is a chronic and progressive neurodegenerative disease, being the most common form of dementia worldwide (60-70% of all cases). AD is considered a protein misfolding disease and the accumulation of amyloid-beta (Aβ) peptide in the brain is considered one of the main hallmark...

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Bibliographic Details
Main Author: Fonseca-Gomes, João Filipe (author)
Format: doctoralThesis
Language:eng
Published: 2020
Subjects:
Neurodegeneração
Doença de Alzheimer
Factor neurotrófico derivado do cérebro
receptor TrkB-FL
fragmento TrkB-ICD
Neurodegeneration
Alzheimer’s Disease
BDNF
TrkB-FL
TrkB-ICD
Teses de doutoramento - 2020
Domínio/Área Científica::Ciências Médicas::Ciências da Saúde
Online Access:http://hdl.handle.net/10451/48478
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/48478

Internet

http://hdl.handle.net/10451/48478

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