Biologic Activity of a Dinuclear Pd(II)-Spermine Complex Toward Human Breast Cancer

A dinuclear palladium-based complex (Pd(2) -Spm) was synthesized and compared with cisplatin (cDDP) on two different human breast cancer cell lines (MCF-7 and MDA-MB-231) as well as toward an untransformed cell line (BJ fibroblasts). The results obtained show that Pd(2) -Spm is more effective agains...

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Bibliographic Details
Main Author: Fiuza, Sónia M. (author)
Other Authors: Holy, Jon (author), Carvalho, Luís A. E. Batista de (author), Marques, Maria P. M. (author)
Format: article
Language:eng
Published: 2011
Subjects:
Androstadienes
Antineoplastic Agents
Breast Neoplasms
Cell Line, Tumor
Cell Proliferation
Cytoskeleton
DNA Damage
Female
Humans
Organometallic Compounds
Palladium
Protein Kinase Inhibitors
Spermine
Online Access:http://hdl.handle.net/10316/45097
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/45097

Internet

http://hdl.handle.net/10316/45097

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