Development of a QSAR models for the prediction of plasma protein binding
One of the most important factors, affecting the pharmacokinetic profile of a drug is binding to plasma protein. As such, this study aimed at the development of a quantitative structure–activity relationship model, to predict the fraction unbound in plasma (fub) for four species, using artificial ne...
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| Formato: | masterThesis |
| Idioma: | eng |
| Publicado em: |
2014
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| Texto completo: | http://hdl.handle.net/10437/5858 |
| País: | Portugal |
| Oai: | oai:recil.ensinolusofona.pt:10437/5858 |