Novel alkynyl substituted 3,4-dihydropyrimidin-2(1H)-one derivatives as potential inhibitors of chorismate mutase

A series of novel alkynyl substituted 3,4-dihydropyrimidin-2(1H)-one (DHPM) derivatives were designed, synthesized and evaluated in vitro as potential inhibitors of chorismate mutase (CM). All these compounds were prepared via a multi-component reaction (MCR) involving sequential I2-mediated Biginel...

Full description

Bibliographic Details
Main Author: Rao, V. Mallikarjuna (author)
Other Authors: Kumar, P. Mahesh (author), Rambabu, D. (author), Kapavarapu, Ravikumar (author), Rani, S. Shobha (author), Misra, Parimal (author), Pal, Manojit (author)
Format: article
Language:eng
Published: 2013
Subjects:
Pyrimidinone
Alkyne
Iodine
Palladium
Chorismate mutase
Online Access:http://hdl.handle.net/10316/26909
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/26909

Internet

http://hdl.handle.net/10316/26909

Similar Items