Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway

Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by interrupting classic pathways of apoptosis. Amyloid-beta (Abeta) peptide has been implicated in the pathogenesis of Alzheimer's disease, where a significant loss of neuron

Bibliographic Details
Main Author: Sola, S (author)
Other Authors: Castro, RE (author), Laires, PA (author), Steer, CJ (author), Rodrigues, CMP (author)
Format: article
Language:eng
Published: 2015
Subjects:
Biochemistry & Molecular Biology
Cell Biology
Medicine, Research & Experimental
Online Access:http://hdl.handle.net/10451/21069
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21069

Internet

http://hdl.handle.net/10451/21069

Similar Items