Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway
Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by interrupting classic pathways of apoptosis. Amyloid-beta (Abeta) peptide has been implicated in the pathogenesis of Alzheimer's disease, where a significant loss of neuron
Autor principal: | |
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Outros Autores: | , , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2015
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10451/21069 |
País: | Portugal |
Oai: | oai:repositorio.ul.pt:10451/21069 |