Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway

Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by interrupting classic pathways of apoptosis. Amyloid-beta (Abeta) peptide has been implicated in the pathogenesis of Alzheimer's disease, where a significant loss of neuron

Detalhes bibliográficos
Autor principal: Sola, S (author)
Outros Autores: Castro, RE (author), Laires, PA (author), Steer, CJ (author), Rodrigues, CMP (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Texto completo:http://hdl.handle.net/10451/21069
País:Portugal
Oai:oai:repositorio.ul.pt:10451/21069