Local delivery of doxorubicin nanocrystals from electrospun nanofibers

The objective of this study is to develop a novel system for local application of DOX either in surgical loci or in a topical application device enabling a controlled release of the drug. The developed system involves the encapsulation of DOX into electrospun polymeric nanofibers. Chosen polymers we...

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Bibliographic Details
Main Author: Ventura, Tatiana (author)
Other Authors: Lúcio, M. (author), Machado, Raul (author), Viseu, T. M. R. (author)
Format: conferencePoster
Language:eng
Published: 2017
Subjects:
Electrospinning
Polymeric nanofibers
Doxorubicin
Controlled drug release
Ciências Médicas::Ciências da Saúde
Ciências Médicas::Biotecnologia Médica
Ciências Naturais::Ciências Físicas
Ciências Naturais::Ciências Químicas
Ciências Naturais::Ciências Biológicas
Engenharia e Tecnologia::Engenharia Química
Engenharia e Tecnologia::Engenharia dos Materiais
Online Access:http://hdl.handle.net/1822/55612
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/55612
Description
Summary:The objective of this study is to develop a novel system for local application of DOX either in surgical loci or in a topical application device enabling a controlled release of the drug. The developed system involves the encapsulation of DOX into electrospun polymeric nanofibers. Chosen polymers were polyoxyethilene (PEO) and polycaprolactone (PCL).

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