Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid beta-peptide-induced apoptosis of PC12 Cells
Amyloid beta-peptide (Abeta)-induced cell death may involve activation of the E2F-1 transcription factor and other cell cycle-related proteins. In previous studies, we have shown that tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates A
Autor principal: | |
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Outros Autores: | , , , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2015
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10451/21071 |
País: | Portugal |
Oai: | oai:repositorio.ul.pt:10451/21071 |