Modulation of translation factor's gene expression by histone deacetylase inhibitors in breast cancer cells

The histone deacetylase inhibitors sodium butyrate (NaBu) and trichostatin A (TSA) exhibit anti-proliferative activity by causing cell cycle arrest and apoptosis. The mechanisms by which NaBu and TSA cause apoptosis and cell cycle arrest are not yet completely clarified, although these agents are kn...

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Detalhes bibliográficos
Autor principal: Gonçalves, João (author)
Outros Autores: Malta-Vacas, Joana (author), Louis, Monette (author), Brault, Laurent (author), Bagrel, Denyse (author), Monteiro, Carolino (author), Brito, Miguel (author)
Formato: article
Idioma:eng
Publicado em: 2014
Assuntos:
Pharmacology
Antineoplastic agents
Apoptosis
Breast neoplasms
Butyrates
Cell cycle
Enzyme inhibitors
Gene expression regulation
Genes, Neoplasm
Histone deacetylase inhibitors
Hydroxamic acids
Peptide chain elongation, Translational
Protein biosynthesis
Tumor cells, Cultured
Texto completo:http://hdl.handle.net/10400.21/3075
País:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/3075

Texto Completo

http://hdl.handle.net/10400.21/3075

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