Electrochemical sensing of the behaviour of oligonucleotide lipoplexes at charged interfaces

Complexes between short oligodeoxynucleotides (ODN) with a variable dGxdCy base composition and liposomes composed of the cationic lipid DOTAP (ODN lipoplexes) were studied by differential pulse voltammetry at a glassy carbon electrode. Since lipoplexes are spontaneously formed by electrostatic inte...

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Bibliographic Details
Main Author: Piedade, J. A. P. (author)
Other Authors: Mano, M. (author), Lima, M. C. Pedroso de (author), Oretskaya, T. S. (author), Oliveira-Brett, A. M. (author)
Format: article
Language:eng
Published: 2004
Subjects:
Voltammetry
Charged interface
Oligonucleotide lipoplex
Cationic liposome
Online Access:http://hdl.handle.net/10316/5119
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5119

Internet

http://hdl.handle.net/10316/5119

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