Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression of osteoarthritis under mechanical stress

Objective: Hereditary hemochromatosis (HH) is a disease caused by mutations in the Hfe gene characterised by systemic iron overload and associated with an increased prevalence of osteoarthritis (OA) but the role of iron overload in the development of OA is still undefined. To further understand the...

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Bibliographic Details
Main Author: Camacho, A. (author)
Other Authors: F. Simao, Marcio (author), Ea, H. -K. (author), Cohen-Solal, M. (author), Richette, P. (author), Branco, J. (author), Cancela, Leonor (author)
Format: article
Language:eng
Published: 2017
Subjects:
Iron overload
Mouse model
Hereditary hemochromatosis
Osteoarthritis
Mechanical stress
Online Access:http://hdl.handle.net/10400.1/9606
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/9606

Internet

http://hdl.handle.net/10400.1/9606

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