Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: implications for calcification-related chronic inflammatory diseases

Calcification-related chronic inflammatory diseases are multifactorial pathological processes, involving a complex interplay between inflammation and calcification events in a positive feed-back loop driving disease progression. Gla-rich protein (GRP) is a vitamin K dependent protein (VKDP) shown to...

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Bibliographic Details
Main Author: Viegas, Carla (author)
Other Authors: Costa, Ruben M. (author), Santos, Lúcia (author), Videira, Paula A. (author), Silva, Zelia (author), Araujo, Nuna C. P. (author), Macedo, Anjos L. (author), Matos, Antonio P. (author), Vermeer, Cees (author), Simes, Dina (author)
Format: article
Language:eng
Published: 2018
Subjects:
Vitamin-K suppresses
Factor-Kappa-B
Vascular calcification
Atherosclerotic plaques
Synovial macrophages
Valve calcification
Articular-cartilage
Matrix vesicles
Osteoarthritis
Expression
Online Access:http://hdl.handle.net/10400.1/11736
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11736

Internet

http://hdl.handle.net/10400.1/11736

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