Prediction of the in vitro permeability determined in caco-2 cells by using artificial neural networks

Caco-2 cells are currently the most used in vitro tool for prediction of the potential oral absorption of new drugs. The existence of computational models based on this data may potentiate the early selection process of new drugs, but the current models are based on a limited number of cases or on a...

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Bibliographic Details
Main Author: Paixão, Paulo (author)
Other Authors: Gouveia, Luís F. (author), Morais, José A. G. (author)
Format: article
Language:eng
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10451/8514
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/8514