Photorelease of incarcerated guests in aqueous solution with phenacyl esters as the trigger
We report the clean, efficient photorelease of a series of carboxylic acids embedded in octa acid (OA) host and protected by a p-hydroxyphenacyl cage. A key role is played by the cage by providing hydrophobicity for entry into the OA enclosure and yet readily removable as a photoactivated protecting...
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| Other Authors: | , , |
| Format: | article |
| Language: | eng |
| Published: |
2015
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| Online Access: | http://hdl.handle.net/10400.1/6564 |
| Country: | Portugal |
| Oai: | oai:sapientia.ualg.pt:10400.1/6564 |
| Summary: | We report the clean, efficient photorelease of a series of carboxylic acids embedded in octa acid (OA) host and protected by a p-hydroxyphenacyl cage. A key role is played by the cage by providing hydrophobicity for entry into the OA enclosure and yet readily removable as a photoactivated protecting group for release from the host. The rapid photo-Favorskii rearrangement of the departing chromophore does not react with the host OA but diminishes hydrophobicity of the OA contents, leading to their facile release into the solvent. |
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